Pardo Gil, Miguel (2022). High prevalence rates of Toxoplasma gondii in cat-hunted small mammals – Evidence for parasite induced behavioural manipulation in the natural environment?. (Thesis). Universität Bern, Bern
|
Text
23pardogil_m.pdf - Thesis Available under License Creative Commons: Attribution (CC-BY 4.0). Download (1MB) | Preview |
Abstract
Toxoplasma gondii causes one of the most frequent parasitic infections in vertebrates on earth. The present study aimed to assess the occurrence of T. gondii infection in cat-hunted wild small mammals, and to determine the circulating T. gondii genotypes in cat prey. There is evidence suggesting that T. gondii may manipulate rodents’ behaviour enhancing transmission to their definitive feline host by facilitating predation. Given that most studies focusing on rodent behavior have been performed under laboratory conditions, we tested this hypothesis in the natural environment. We analysed 157 cat-hunted wild small mammals of six different species from Switzerland. Brain and skeletal muscle samples from each animal were tested for T. gondii DNA by PCR, and positive samples were genotyped using a multilocus sequence typing approach. The prevalence of T. gondii in cat-hunted Arvicola amphibius s.l. was 11.1%, 14.6% in Apodemus spp., 13.6% in Myodes glareolus, 6.7% in Crocidura russula, and 0% in Microtus arvalis and Sorex sp. All completely genotyped T. gondii parasites, exhibited the ToxoDB #3 genotype, a Type II variant. We additionally analysed 48 trap-captured A. amphibius s.l., which all tested negative for T. gondii infection, contrasting with the higher prevalence in cat-hunted A. amphibius s.l. These results provide evidence that T. gondii infected rodents are at higher risk to be predated by cats and therewith support the behaviour manipulation hypothesis.
| Item Type: | Thesis |
|---|---|
| Dissertation Type: | Single |
| Date of Defense: | 8 December 2022 |
| Subjects: | 500 Science > 590 Animals (Zoology) 600 Technology > 610 Medicine & health |
| Institute / Center: | 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Parasitology |
| Depositing User: | Sarah Stalder |
| Date Deposited: | 11 Oct 2023 11:31 |
| Last Modified: | 08 Dec 2023 23:25 |
| URI: | https://boristheses.unibe.ch/id/eprint/4584 |
Actions (login required)
 |
View Item |