BORIS Theses

BORIS Theses
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Patterns of airway obstruction of non-acquired origin in children with and without major congenital anomalies

Gonçalves Dias, Rodrigo (2021). Patterns of airway obstruction of non-acquired origin in children with and without major congenital anomalies. (Thesis). Universität Bern, Bern

21goncalves-dias_r.pdf - Thesis
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Major congenital anomalies are known to play a role in the management and prognosis of airway obstruction. Most studies assess acquired forms of airway obstruction. Data on congenital or otherwise non-acquired forms of airway obstruction is sparse. In this retrospective, single-institution cohort study, we sought to evaluate and compare the patterns of airway obstruction in children with and without major congenital anomalies, and to assess the impact of management and outcome, irrespective of aetiology. Fifty-five patients were included, 23 with and 32 without underlying major congenital anomalies. Multilevel airway obstruction (usually affecting the nasopharynx, oropharynx, and the trachea) was more common in children with congenital anomalies (91% vs. 41%, p < .001). Consequently, these children required more frequent and earlier surgical management, especially tracheostomy and adenotonsillar surgery. Conclusions: Major congenital anomalies are associated with multilevel airway obstruction and poor functional prognosis. A simple clinical definition considering impact of major congenital anomalies on development and growth may help guide management plans following endoscopic evaluation of the entire airway and flanked by multidisciplinary discussions.

Item Type: Thesis
Dissertation Type: Single
Date of Defense: 20 October 2021
Subjects: 600 Technology > 610 Medicine & health
Institute / Center: 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)
Depositing User: Hammer Igor
Date Deposited: 09 Jan 2023 15:45
Last Modified: 10 Jan 2023 01:30

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