Huguenin-Dezot, Michaël Alain (2024). Glued suture-less peritoneum closure in laparoscopic inguinal hernia repair reduces acute postoperative pain. (Thesis). Universität Bern, Bern
|
Text
24huguenin_m.pdf - Thesis Available under License Creative Commons: Attribution (CC-BY 4.0). Download (1MB) | Preview |
Abstract
Inguinal hernia repair is performed more than 20 million times per annum, representing a significant health and economic burden. Over the last three decades, significant technical advances have started to reduce the invasiveness of these surgeries, which translated to better recovery and reduced costs. Here we bring forward a novel surgical technique using a biodegradable cyanoacrylate glue instead of a traumatic suture to close the peritoneum, which is a highly innervated tissue layer, at the end of endoscopy hernia surgery. To test how this affects the invasiveness of hernia surgery, we conducted a cohort study. A total of 183 patients that underwent minimally invasive hernia repair, and the peritoneum was closed with either a conventional traumatic suture (n=126, 68.9%) or our novel approach using glue (n=57, 31.1%). The proportion of patients experiencing acute pain after surgery was significantly reduced (36.8 vs. 54.0%, p=0.032) by using glue instead of a suture. In accordance, the mean pain level was higher in the suture group (VAS= 1.5 vs. 1.3, p=0.029) and more patients were still using painkillers (77.9 vs. 52.4%, p=0.023). Furthermore, the rate of complications was not increased in the glue group. Using multivariate regressions, we identified that using a traumatic suture was an independent predictor of acute postoperative pain (OR 2.0, 95%-CI 1.1-3.9, p=0.042). In conclusion, suture-less glue closure of the peritoneum is innovative, safe, less painful, and possibly leads to enhanced recovery and decreased health costs.
| Item Type: | Thesis |
|---|---|
| Dissertation Type: | Single |
| Date of Defense: | 26 June 2024 |
| Subjects: | 600 Technology > 610 Medicine & health |
| Institute / Center: | 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine |
| Depositing User: | Sarah Stalder |
| Date Deposited: | 05 Feb 2025 07:44 |
| Last Modified: | 05 Feb 2025 07:44 |
| URI: | https://boristheses.unibe.ch/id/eprint/5792 |
Actions (login required)
 |
View Item |